The term "Tu abuela" is a very commonly used Puerto Rican term that depicts a large number of uses, the most common of which is a comeback.

While it's most common usage is in a comeback, it can also be the answer to a question, establish you dont want to continue the conversation, break the ice, initiate a romantic sequence, be an adjective, an answer to a knock knock joke, or just literally refer to a person's grandma; tu abuela in this sense is a little like Por las nalgas.

When you eat dirt for the first time and leave your family to build a shack in the woods