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Physical ailment characterized by the repeated expulsion of absolutely foul, often sulfuric and environmentally destructive gasses from one's rectum, especially in libraries, classrooms and other public spaces. cf. "toxic shock syndrome", which can, incidentally, result from contact with someone carrying a particularly severe case of TFS (toxic fart syndrome).
"Dude that smell emanating from your rectum has increased global temperature by a half a degree celsius! I think you've got the toxic fart syndrome..."

"I was in the library yesterday and people started complaining at the front desk of a natural gas leak. Little did they know that it was the result of the ejection of the very unnatural gasses of my Toxic Fart Syndrome."
by Hominid54 March 24, 2014
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