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When something is so intensely something, it is literally THE ONLY thing of it's kind in specific genre. Can be good, bad or indifferent.
I have THE ONLY headache.

I have to take THE ONLY piss.

She has THE ONLY eyes, dude.
by Faith Alana Alastair February 25, 2009
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Oct 31 Word of the Day
1. acronym for Laugh Out Loud + sob -- an expression for something that makes you lol and cry at the same time.

2. acronym for Laugh Out Loud, Son of a Bitch. An expression of bitter anger over something funny.
That fatal clown car accident made me lolsob-- clown cars are funny but my best friend was driving.
by duenna9 October 12, 2009
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