The 4 most brutal, extreme, and amazing metal bands ever. They include:
Metallica
Megadeth
Slayer
Anthrax
They're either thrash, heavy, or speed metal.
When it comes to The Big 4, there fans go like this:
Metallica fan- Megadeth sucks!
Megadeth fan- Metallica sucks!
Slayer fan- Like Slayer or I'll slay you!
Anthrax fan- Anthrax is cool.
by Metalhead261 March 28, 2011
The Big 4 refers to the stuck-up snob universities in the Philippines. Imagine the Ivy League but in development. It consists of the University of the Philippines, De La Salle University, THE Ateneo de Manila University, and University of Santo Tomas. Students from these universities are either militant activists or sons of wealthy capitalists.
Friend A: "Where do you wanna study ba for college?"
Friend B: "Not sure pa but I applied sa Big 4."
Friend A: *Whispers* "Ah, ha ha ha.... Sige, I got to go."
by domimonite December 24, 2020
A penis that has 4 heads and talk to you in the middle of the night
Am I dreaming or is my big 4 talking to me?
by Swagger master October 19, 2013
In the CB slanguage:

1. Hi there!

2. Enthusiastic agreement.
1. I just wanted to say a big 10-4 to ya!

2. That's a big 10-4!
by Downstrike May 29, 2004
Legend. Somebody who has a small cock but likes to shag. Clearly fit as fuck.
OMG, here comes Big Daddy 4 Incher, what a fitty
by ItsYaBoi99 November 27, 2019
be careful they might bust on your eyes and eat you like apple pie
person 1: LOOK ITS THE 4 BIG GUYS
persin 2: THEY ARE GOING TO BUST ON MY EYES
by thejamesywaamesy December 14, 2021