The art of tucking your testicles between your legs and stuffing your own scrotum into your rectum. The final act is farting out the scrotum.
Josh: What are you up to tonight, Bobby?
Bobby: I think I’m gonna go home, drink a few beers and do a little Stuff & Puff.

Josh: What is that?
Bobby: I’m gonna stuff my nuts into my ass and fart them out!
by Catwrencher October 5, 2018
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Any drug that can be smoked.
Cop 1: Did you find anything in your vehicle search?
Cop 2: Yeah, found a couple rap crap cd's and a small bag of puff stuff.
by boo&brasen January 27, 2013
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