1. An actor who portrayed Uncle Jesse on Full House from 1987-1995, he originally became famous from starring in a soap opera called general hospital, and was on a show recently called ER, and has also done some Broadway shows in the early 2000's.

2. The sexiest man alive, great personality and a sultry voice.
"Oh my god who is that hot guy on full house?"
"Oh that's uncle Jesse aka John stamos aka the sexiest man alive"
by Madison P April 29, 2015
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Showing "John Stamos" like qualities
Hey brah, have you seen that bad ass Ryan guy... He's got mad Stamos Status!
by Albyno Ryno October 9, 2011
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The semen of a greek male.
When Stavros shot his hot stamos sauce over her chest, she was heard to shout, "Opah!"
by FH Jon January 11, 2006
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it is quite possible that john stamos is the coolest individual to walk the earth. he has it all, from sweet hair to good looks to tight pants. definitely the best character from full house, aka uncle jesse. the "epitomy of coolness", john stamos is the guy every girl wants to date. every guy wants him as their best friend. he knows whats hip, cool, and he teaches DJ, stephanie, and michelle every moral they've ever learned.
john stamos` ex-wifes name is rebecca. my name is rebecca. coincidence? i think not. marry me, john stamos.

john stamos is the hottest guy ever, next to brad pitt.

jeez, look at that guy`s hair. he looks exactly like john stamos. sweet.
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1. Uncle Jessie from Full House
2. Taking a poop, while masterbating, and eating a bowl of cereal. A variation of the Bob Saget.
I did a John Stamos after watching full house.
by L. Roman July 16, 2006
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When you have two pair on the turn in poker and there's a chance that a full house will be revealed.
"I went for it because of the Stamos potential."
by soda September 10, 2004
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