Top definition
A disease worse than measles, mumps, and rubella. If a member of your Oregon Trail team contracts spyder lumps, its game the fuck over. Forget trying to forge a river or go hunting for deer, spyder lumps shows no mercy. There is no known vaccine but some say there is a cure to be found in a library off of decatur street in Philidelphia. Ask the man who grew up there, played fewtball there and used to be a carpenter for help.
When the doctor came back into the room, I could tell by the look on his face it wasn't good. My sigh of relief when he said it wasn't AIDS was premature...for it was, the spyder lumps.
by spyder lumps November 22, 2011
Get the mug
Get a Spyder Lumps mug for your Aunt Larisa.