Top definition
(of a person on LSD) a rumbling or dull discomfort in the bowels indicating that one has to poop; an experience entirely different from that of the Vyvanse cleanse
"We need to get on our way to the creek before we come up."
"Wait... Oh, man, I think I'm already there. I've got spiritual bowel syndrome."
"Shit."
by Kashmir Cardigan August 26, 2017
Get the mug
Get a Spiritual Bowel Syndrome mug for your barber Trump.