Awesomely handsome brothers-in-law who are married to equally beautiful sisters.
Tan Keith is the best Sista-brotha this side of the James River. Our wives, whom are sisters, are so lucky to be married to us.
by DJ Tan-NERD September 19, 2020
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apparently meaning a very sassy girl.

verb: sista sledgin' (meaning smarting off, dissing, etc.)
Don't pop that attitude with me sista sledge!

Yes Tamara was totally sista sledgin' me today.
by Montyy_18 May 20, 2011
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Two, or more, unusually close girlfriends. They are highly suspected of "Twizza"-ing in there spare time...
A Twizza can find love in another females eyes and not think nothing of it.

Those Twizza Sista's sure are close
by CLO-Dawg August 19, 2010
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Two girls that have sexual intercourse with the same gentleman.
Amber: Hey Brittney, you screwed Matt?!? Yay! We are Mista Sista's!!

Brittney: Ya!! I heard you did too! He was awesome!!!
by DURB February 19, 2015
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closer than a friend, not as annoying as a sister.
oh shes just my sista-frien' we keep it fo' real. my sista from another mister.
by Alex & Danielle June 13, 2008
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