An affectionate word for a sister, or someone regarded as a sister. It can be a nickname given to someone who acts sisterly, kind, sweet, and caring.

It's also used as an affectionate word by many in the transgender community for transgender women who love being super girly, cute, and sweet a lot more than average. It can be a kink, or an interest to them.

Since it started as a word for sister it was later used as a derogatory word by sexist people that believe if you were born a guy you shouldn't be effeminate.

A degrading word for a man who is feminine, might wear women’s clothes, prefers to be themselves over a stereotypical man. Probably has issues with self Image and insecurities.
Might come off weak but will most likely tell you wear to go if they must.

A derogatory term used to describe a homosexual (man).

2. heterosexual man acting in a feminine way

*commonly used in the south

A very close and dear friend. Someone who is, or whom you consider, to be a sister. Someone who will never let you down and be by your side for life.

just a cute word to call your sisters

a little weak wimpy guy who loves to create drama to make up for sad weak miserable existence. No lifer. A perso whos weak.

Originally defined as "wimp", "pussy" or "weak" the word sissy has morphed into the perfect def'n of a Brazilian footballer.