Someone Extremely high, on their own personal mission, totally blowing it; obviously high having lots of fun without a care.
Billy is showed up with his truck entirely repainted, he must be on a sick one
by Sickfn December 03, 2016
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This word combination refers to the state of a person when on drugs.
tripper- "Oh, I'm on a sick one!"
by beautiful biotch February 15, 2010
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When a rancher goes old-school in castrating sheep with his teeth.
Rowdy is one sick cowboy, a shepherd with ball-less sheep thanks to his incisors
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When your friends say something that is not true or extremely retarded or do something that is extremely retarded
Person: "You have as many brain cells as a fucking ant"
You: "sick one mate"
by Big Mr Tryhard April 14, 2021
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