1: Crazy as in not completely mentally stable
2: Crazy as in Funny, humorous
1) You ever seen that movie Fatal Attraction? Glenn Close character is Shot-out
2) You catch that comedy show Dave Chappelle put on, dude is funny is hell. He is shot-out
by KBoogie00 December 21, 2011
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"Out of it" or brain addled from heavy drug consumption. Referring to heroin it literally means "shot out" of a person's mind.
Don't trust that guy's memory, he's shot out.
by addictmentality May 21, 2015
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When someone is shot out it means they are permanently mentally fried from doing too many drugs.
Damn.. I miss the old Cassie.. she’s so shot out now she can’t even hold a normal conversation..
by littleforestpeach January 10, 2020
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a term for person who has did way to many illicit street drugs for way too many years and is probably still using them. Usually someone who is a i,v, drug userand that NO BODYS HOME look in there eyes.

Somebody who is such a low level garbage junkie they will take any type drug they can get there hands on
Yo bro Jigs so SHOT OUT he just took a whole bottle of No Dose tryin to get high.
by Ghettoking215 February 10, 2019
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When someone does something stupid, crazy or careless.
Yo, Jimmy's drunk as shit running in the street with no shirt on. "He's Shot Out!
by Moe120 June 24, 2011
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