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What you say when things go so wrong that there's no chance that they could get better or when you mess something up to the point that you cant fix it. Saying this is usually accompanied by throwing your hands in the air and turning away. This is usually an over-reaction.
"Hey, I just spilled sour milk all over the carpet... Screw it, sell the house!"

"I think I left my kid at the grocery store... Sell the house!"
by IThinkImFunny June 11, 2013
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