SIU = Southern Illinois University, located in Carbondale, Illinois. Home of the Salukis!
SIU basketball dominates the Missouri Valley.

SIU is one of the top party schools in the nation.
by Grey Dawg November 05, 2009
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Person 1: Ow, I bumped into that wall.
Person 2: Man, SIU go beast it
by Lynbrook Viking April 03, 2006
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Acronym for Special Investigation Unit for law enforcement/prosecutors and insurance compaines
When that boatload of coal claimed whiplash, they called SIU in to videotape them playing basketball
by Teabag April 05, 2006
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Acronym for 'step it up' meaning for one to reach a new/higher level then previously on.

Commonly used in forums and online gaming.
Guy 1: Dude, your bottom of the team. SIU

Guy 2: Hey, I'm new, I'm trying my best okay!
by Charlag June 02, 2011
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a unit of measurement equalling 5'0"
Slocum Hall's rotunda is about 3 sius tall.
by Brandice February 25, 2003
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A man who's loved by everyone. He's remembered by his amazing muscles and his long luscious flowing hair. He loves to laugh and make others laugh as well. People are mesmerized by astonishing looks. Definitely a man deserves 10/10
by Husky4life March 15, 2017
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she teach at LSC. she always say 'eh'
A: are u siu 姐?
B: ehh...
A: you are.
by kil.me.321 October 28, 2019
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