A lesbian talk show host and comedienne. Surly, smart, and funny. For some reason, she's become a punching bag for a lot of groups--possibly because they're unnerved that someone who is gay and conventionally unattractive, could be so successful in a media career.
Kevin: Rosie O'Donnell is a big fat whale dyke!
Joe: Don't you wish you had her fame, though?
Kevin: ...I guess so.
Joe: And what about her hot wife?
Kevin: She's a stupid dyke too.
Joe: And she's hot. WAY hotter than your wife, and you know it.
Kevin: Shut up!
by sunsetninja March 31, 2010
When a female is fat, loud , annoying and has a very ugly face, and also being very ugly on the inside. An overall horrible person.
"Man that bitch was faaaat!" "Yeah , she was really annoying too and such a bitch." "She was definitely Rosie O'Donnell ugly"
by Donald Trump 2 November 1, 2007
To lose ones erection by viewing vile, disgusting pictures of grotesque naked women, or looking upon the large rear side of a bent over woman. A sure cure for making a hard on disappear in an awkward moment. Such pictures and other stimuli can be found useful and is first step in treating prolonged Viagra and other erectile medication side affects.
Patient: "Dr Phil, I woke up after a night out and hitting hard on the Viagra and now I can't get rid of my wood. Should I come into your office or to an emergency room? "

Dr Phil: "Before you come down to the office or emergency room. I want you to try something that we in the medical profession commonly refer to as a Rose Ann Barr Naked - Also known as Rosie O'Donnell naked. Otherwise known as a Cow Heather, or just a f#$&ing cow.

What you need to do is, try walking down East Carson and find a fat ass cow to ogle. If you don't want to leave your home then sit on your couch and turn on the television and watch The View. Watching that cow Rosie O'Donnell should alleve you of your erection. I know it always does for me. If that doesn't work, then we have other less invasive methods we can try. Such as going to the local frozen yogurt shop and viewing a few hogs, I mean cows there. Anyway, good luck."
by T_rump_supporter November 7, 2010
Def 1: Someone who is fat and extremely ugly. Water on the brain big head. And also not a "good" person. He/she is rude, hateful and nasty. If you have an opinion different from he/she, he/she will be even more nasty; Vile mean spirited person.
Def 2: An angry midget wrestler.
Ex 1:

P1: Damn! Mrs. Collington is the worst PE substitute ever! She call me slow and she made me run mile when she couldn't even run!!! Plus she is a f$$king landwhale!!!
P2: Did you mean Mrs. Rosie O'Donnell?


P1: Can you imagine if Tom Cruise gain some weight and join WWE (world wrestling entertainment)?
P2: Fuck! We need no Rosie O'Donnell to wrestle!!!
by Dr. Gingerbreadkeemstar February 2, 2018