14
A males unshaved genital area. The male has not shaved for quite some time now and his pubic hair is long and puffy.
Samantha: Did you go down on Kyle ?
Nicole: he wanted me to, and i was down. However when i pulled down his pants i saw a puffer fish and totally freaked!
by Dj AF May 24, 2010
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15
Whoever ate the first pufferfish must have been adventurous. (And most likely died shortly thereafter.) Almost all pufferfish contain tetrodotoxin, a deadly toxin that is up to 1,200 times more poisonous than cyanide. The poison in one pufferfish is enough to wipe out 30 humans, and there’s no known antidote.
P1: what you eating?

P2: pufferfish
by ... Zjdbckdnznsjd March 15, 2019
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16
my extremely cute girlfriend, who smokes adorably and looks like a cute little pufferfish.
she smokes like a pufferfish?! lol
by aprils girlfriend June 16, 2009
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17
Someone who is fat beyond comprehension.
Yo you saw that guy on the scooter, he looked like a Pufferfish.
by YehNameJeff June 28, 2016
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18
A deplorable, and hideously ugly girl with huge lips and puffy cheeks. Also see annoying piece of shit.
Tara...hahahahahhahahahhahaha
by Slash September 16, 2003
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19
When you throw up in your mouth so much that it should come out, but you manage to keep it in. You then try to get people's attention and get them to understand that you have a mouthful of puke and that you need their help by waving frantically and doing your best to imitate vomiting without opening your mouth
I was on the bus this morning, and pufferfished. So embarassing, no one could figure out what was wrong. They did when I got off the bus, though.
by hyawkus March 29, 2016
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20
A person who lies about being pregnant
April fools I'm not actually pregnant, Karen your such a pufferfish.
by Mcroy Drew August 17, 2020
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