A condition where your favorite character is always the main character, no matter how annoying and unattractive.
If Bella Swan is your favorite character in Twilight, you're obviously suffering from a major case of protagonitis.
by Dulce et Utile July 16, 2015
An unfortunate condition where a person in real life has characteristics not unlike the ones a protagonist in a wish-fulfillment story would have. The symptoms of someone with Protagonitis are as follows: has a dark traumatic past, has a secret power that nobody knows about, is given some special power or talent, has a ridiculous amount of luck, and is extremely attractive to many members of the opposite sex for no apparent reason.
by Bentoboxing December 02, 2019
a condition that makes the sufferer unable to resist games, books, and movies that feature an author as the main character.
He had writer protagonitis, and was therefore unable to resist buying Alan Wake for xbox360, Steven King's Misery, or Finding Forrester.
by Rotzo January 06, 2006