Top definition
Prescription antihistamine used to treat nausea, dizziness, and other allergic reactions.
Last week when I had the flu, the doctor prescribed me promethazine for my dizziness and nausea.
by PharmSalesGirl February 06, 2013
Get a Promethazine mug for your papa Callisto.
Jul 26 Word of the Day
Noun: a friend who is usually only called upon by a friend when a more primary/prominent friend is unavailable.

Taken from the term “second string” in an athletic competition situation. In football, if the star quarterback gets injured during a play, the second string is called off the bench to replace him/her. A “Second String Friend” is essentially benched until needed, if ever.

Synonyms: Plan B, Second Choice, Secondary Friend, Benched Until Needed
I got a call from X the other night. She had an extra ticket to a concert she bought for a friend, but they couldn’t make it so she called me to ask if I wanted to go because I am her Second String Friend.
by Deus-ex-machina August 26, 2020
Get the Second String Friend neck gaiter and mug.
2
normally used to make purple drank, but if you wanna trip even harder soak your weed in promethazine before you smoke it. give it a few minutes to dry beore you load it into your pipe. gives you all the effects of drinking lean except it's more intense and you feel it faster because you smoked it.
lil wayne dips his bud in promethazine in one of his songs
by n eazy January 13, 2008
Get a promethazine mug for your cousin Manafort.
3
promethazine is purple drank comin mainly from Houston, TX. its basically cough syrup that u mix w/ either a bottle of soft drink(whichever u prefer, usually sprite of any sort)that, or u mix w/ alcohol. and it gives u a leaned out kinda feelin, its how us texan folkz get throwed ya heard?

also, see the word, drank
"Say mayn, u got a deuce of that promethazine?"
by Joseph Lam April 30, 2006
Get a promethazine mug for your sister-in-law Riley.
4
Promethazine is commonly used anti-emetic drug. Promethazine is also slang for wine in health care worker circles. Specifically Paramedics use this term to describe drinking wine of any sort.
"Hey Laura, what are you doing tonight?" "I dunno I was thinking about going home and drinking a bottle of promethazine"
by Meeeeeeeeedic 1 April 16, 2007
Get the promethazine neck gaiter and mug.