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The depression sometimes felt after sexual intercourse or masturbation.
Jonathan suffered from post-coital depression this morning after cumming his balls, brains and spinal fluids out last night in an orgy of procrasturbation.

After losing her virginity in an orgasm filled, yet loveless bangathon in her dorm room last night, Dafny felt a mixture regret, post-coital depression and vaginal soreness.

News that his baby tank was pregnant again with more fuck product only deepened Harry's weeks long post-coital depression.
by AYYFRON October 19, 2009
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The traumatic realization that every girl you have had intercourse with is a nasty whore, and that every interaction leading up to and during the act was a waste of time and energy. Those who suffer from Post-Coital depression are usually attractive and presented with plenty of sexual opportunities.
Summer : Hey, what's wrong with Morty? I thought he was finally happy now that he's popular.
Rick : He finally hooked up with Jessica and is suffering from Post-Coital Depression.
by pickled rick September 29, 2017
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