Warning of a negative outcome if you were to provoke a situation.

Similar to don't poke the bear but better

"Don't poke the bull, or your gunna get the horns"

When a guy takes two fingers and pokes them into a girls ass, then into her mouth.

The act of inserting objects into ones exposed ass crack.

The famous flanagan poke is often seen as an innocent hello to the untrained eye when in fact it is something much more underhand. It is a signal of sexual intent and it basically means she wants to ravage your naked body. Poking back is like a contract agreement, promising flanagan that she can get her dirty scouse hands on you.

When your veins or another person's veins are hard to reach, particularly when drawing blood.

To have sexual relations with a type of fruit by either hollowing a hole and repetitively thrusting it, or cutting the fruit into slices and forming a frussy by taping the slices into a round shape for sexual pleasure.

Give her a poke.
When someone sees a two hole that isn't the best looking but still bangable.