A very effective way of doing most drugs. Basically, you stick it up your butt.

There's a stigma against it because a lot of people are scared of their own rectums. Ultimately, it's a matter of personal preference; if you're adventurous, try it- it works great. If not, there's plenty of other methods that don't make you feel violated.

Mercury retrograde is the act of taking a shit whilst mooning one or more human beings. Your day can typically being going well, according to your horoscope, until you are forced into witnessing Mercury retrograde. Performing Mercury retrograde will often speed the astrological cycle forward for the individual performing the Mercury retrograde, bringing about happy and fruitful times to come.

administering the drug extasy, (MDMA), rectally. The more the capillary exposure, the higher you get

The insertion or other voluntary introduction of foreign matter into the anus or vaginal cavity for the sole purpose of recreational misuse(or use) of said item/substance. Similar to butt chugging, with the exception of using non-liquidous matter instead of alcoholic beverages.

The anal administration of any drug. Most commonly done with MDMA, DMT, or 2cb

Nominalised form of the infitive 'to plug'. The gerund form broadens its contextual use and allows its employment in noun, gerund, and participle clauses.

A way to smuggle drugs without getting caught by sniffer dogs.
A woman usually plugs with the substances in her vagina and a man his anus (the drugs aren’t exposed to flesh, of course).