A question one asks when one is told of a very ugly girl. In effect, it is asking whether this girl should take to wearing a paper sack over her head, or whether she's so incredibly fuck-awful that the only thing left is for her to suffocate herself with a plastic bag.
Dude, I met this chick at a Wendy's the other night. She was super into me. Too bad she was fugly...

How bad? Like, paper or plastic?
by Jamocahchip June 10, 2010
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The ridiculous invention of various elderly citizens who think that if their milk spills in a paper bag inside of a plastic bag, their 1955 Ford won't be ruined. Also, it is easier to carry/stand up/heavier, all of which are not at all true. A cashier's worst nightmare.
Cashier: "Hi, how are you?"
Customer: "Paper in plastic please, and don't make it too heavy."
Cashier: eyeroll
by grocerystorecashiersofamerica January 19, 2011
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Expression that denotes a mental shock, particularly when somebody asks something totally new in a difficult, alien or unknown dialect.

It originated from the shocking experience of immigrants shopping in an American supermarket, when asked about paper or plastic bags; it is a common first culture shock.
1) I didn´t understand a word he was saying. It was like a different language. Paper or plastic?!
by Fernando Gonzalez October 14, 2005
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Referring to safe sex practices, requiring either STD test results (paper) or condom (plastic).
I told my new boyfriend that when we get ready to have sex, it's either paper or plastic, that's my policy.
by myhappydestiny September 15, 2010
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