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I was working on my car and couldn't get the head bolts undone, so I sprayed some Panther Piss on that bad boy and they came straight out !
by Chewy the Wookie December 16, 2011
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A particularly vile alcohol. Worse than run-of-the-mill bad alcohol due to an offending odor or flavor. Often applied to cheap wine, booze, or beer whose only redeeming factor is that it can get you drunk.
Sure, Coors Light is panther piss, but after 6 or 7, you won't care.
by Old Joe Bob April 14, 2006
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worthless diluted liquid, such as beer or gasoline.
1. I was 17 when I was visiting my cousin in Memphis. He gave me a can of Coors beer. I tasted it for the first time. It tasted like industrial slop water. That or maybe panther piss. The worst beer in the universe.

2. I was driving on the New York State side of the Niagara Falls area and my car's tank was down about half. I wanted to get gaased up on the American side because Canada has a lot of gas brands of their own and I didn't know how suitable they are to my car's engine. I saw virtually no major brand gas stations on the highway, so when I saw a sign leading to a gas station at the Ticonderoga Indian reservation I took the exit. I fueled up, the gasoline brand was exclusive to the Iroqouis Confederacy. I was afraid that I was tanking up with panther piss but the gas was really good. My car operated nicely. No bucking and snorting. No problemo. Later that afternoon I crossed the border into Canada, where the hotel I reserved a room at was located.
by I Saw U2 Live Twice November 12, 2007
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A bar on the corner of 4th and Lincoln in Charleston, IL. A place where Irish car bombs come in plastic cups with plastic shot glasses that won't sink to the bottom of the beer and cost $8. Formerly known as Styx.
Hey dude. Let's go down to the Panther Piss and get some $8 Irish car bombs.
by ElMonoDelMar December 17, 2007
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