When your homie starts playing that one radio station that you can't stand just to piss you off and you end up beating his ass
Man, ed kept playing that damn nickleback station so I started pandora boxing him till he quit
by GrimThaReaper December 26, 2017
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The effect that transcends one's curiosity into an overactive drive/need to experience something, regardless of the ending possibilities. It is different from peer pressure since it does not require external forces, but is similar to physiological effects, such as being horny.
A: I think I wanna get a prostate exam, just to see what it's like
B: That's the Pandora's Box Effect, dude. Don't fall for it.

A few days later

A: I got a prostate exam.
B: You look a little different.
A: You think?
by NTRP January 06, 2021
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