the feeling that no matter what you do something is always somehow wrong—that any attempt to make your way comfortably through the world will only end up crossing some invisible taboo—as if there’s some obvious way forward that everybody else can see but you and they're all trying to help, but you keep disappointing them.

when you're hungover as shit after a spending a night drunk as a skunk

It means a favor..

Irish slang short for paranoid.

get paro means, to get drunk/pissed.
the state in which someone becomes after they drink excessive amounts of alcohol

someone who is scared and/or paranoid

When a piece of software crashes, but doesn't give any notification. It simply disappears, with no warning, and no opportunity to save your work