It is a gamers phrase, where the 1337 player pwns the noobie and then the leet player says OwNeD pLz Ty or you get heavily slaughtered, ty for trying.

A pick me is a woman that is willing to do anything for male approval. She will embarrass or throw other women under the bus to achieve this goal. The unfortunate thing about a pick me is usually the men they are trying to seek approval from are of poor quality and treat women badly, leaving little real benefit for the pick me.