Verb: To osbourne something is to brutally maul and/or decapitate something. Named after George Osbourne, Chancellor of the Exchequer from 2010, who made a lot of spending cuts.

when you're hungover as shit after a spending a night drunk as a skunk

(verb) To take what would normally be a simple and straightforward task or process and screw it up royally. To mess up an operation which seems like a sure thing. To choke.

The guy who always fucks shit up...