Ope is the Midwestern way of acknowledging another person or thing that they have encountered.

Someone people turn to when they're sad who makes them feel better.

What Eminem actually says in his

Lose Yourself verse.

It's a Midwest thing. When someone cuts in front of you rudely, when you are surprised, when you bump into someone, or when something is offensively funny, you use the word ope.

Something you say when you are surprised

(noun) -An interjection of surprise after an unexpected event occured. It can be for either bad or good connotation depending on the situation.

1: A reaction for something small but silly happening.

2: Said after a witty remark.