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OFIFU is the acronym of the phrase "Oh Fuck I Fucked Up".
It can be used in replacement for your friends name when they do something stupid aka fuck up!

This also can be molded into various forms:

Ofifian: a race of people who fuck up
Ofifed or Ofifud: both the verb form of Ofifu
"fucking ofifu, your such a dumb bitch!"
"I think victor is a ofifian he is always fucking up"
"Dick my condom rip when i was in this bitch i ofifed.
by Arzebby June 14, 2011
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May 3 Word of the Day
Internet persona(s) who happens to follow you and you happen to follow them back and maintain communication with and have a mutual liking for eachother whether it be friendship wise, etc. (Mutuals if more than one mutual)
Monica: Oh yay! I made a new mutual today because we started following & talking to eachother on twitter and we like eachother (so it seems).
by qtheresurrection March 25, 2015
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