Top definition
That unnerving feeling when something has gone horribly wrong while doing work and your anus tightens up in a flinching and constipated way. It's a form of panic attack when you realise your life / career just ended and you go into a wild panic to try rectify the situation before you get found out.
Boss: While you're updating all the systems, if it goes pear shaped, don't have a nipsy twitch, just get it fixed!

or

Worker: I hit the red button instead of the green one and suddenly felt my nipsy twitch.
by the_minidude June 17, 2014
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Jun 24 Word of the Day
An exclamation made when your friends or family are teasing you to a point where you can't handle it anymore and a hissy fit is in order.

Derived from a YouTube user's famed outburst following Britney's lackluster performance at the 2007 VMA's.
Sarah: 'OMG Susan, I can't believe you are wearing the same skirt as yesterday. Oh, and by the way, EVERYONE knows what you did with Kevin on the weekend. Plus you look a little fat, are you retaining water?'

Susan: 'LEAVE BRITNEY ALONE!'
by Billy Chickenhole September 15, 2007
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