Top definition
A relationship phenomenon where a man first shows interest to another person and that other person begins to show interest in them. In this phenomenon there is the complete opposite of what is expected, the man who first showed interest backs-offs and completely loses interest. The person who started to like this man is left dumbfounded at the situation.
The girl layed in bed crying all night after the Nick-A-lexis syndrome strikes again.
by medschoolheartbreak June 28, 2011
Get the mug
Get a Nick-A-lexis Syndrome mug for your mama Julia.