Top definition
The new, seemingly cool, pronunciation of "mother fucker". Stolen from the movie "Big Money Hustlas".
That's my money, muthafacko.

'Sup, muthafacko?

What are you muthafackos up to this fine afternoon?
by dcomposed December 13, 2003
Get a Muthafacko mug for your Facebook friend Paul.
Aug 11 Word of the Day
A phrase to describe someone who is cognitively degenerating. Synonym of "going off the deep end". Can have varying degrees of severity.

Reference to the song "Hey You" by Pink Floyd. The line "and the worms ate into his brain" makes no sense in an otherwise linear and literal narration throughout the lyrics.
"My boyfriend has a total case of brain worms. He told me the cat was bugged so the Feds could listen in on us having sex..."

or

"You totally stumbled over that entire sentence. Can't speak English all of a sudden? What, do you have brain worms?"
by _Jez_ October 03, 2009
Get the brain worms neck gaiter and mug.
3
a cleaner, funnier form of "motha-fucka". used by the Psychopathic artists.
My money mutha-fackos!
by ninja September 18, 2003
Get a mutha-facko mug for your barber Rihanna.
4
term used commonly by juggalos, juggalettes, ICP, etc. same as mother fucker
Man, that mutha facko wont share the faygo!
by tweemo April 20, 2003
Get a mutha facko mug for your grandma Beatrix.
5
The history of mutha facko is a short one. It was first used by Violent J of Insane Clown Posse. He used it also in the juggalo movie Big Money Hustlas. It picked up usage then and los and lettes around started using it instead of mutha fucker.

MFL,
Juggalo Xtreme
by Juggalo Xtreme September 01, 2004
Get a Mutha Facko mug for your brother Callisto.
6
1) A close friend/ associate. 2) A bitch / slut 3) Will (see also dcomposed)
What's poopin', Muthafacko?
by morethanthesumofmyparts October 15, 2003
Get a Muthafacko mug for your dog Jerry.