On Twitter, short for "mutual follower," that is, a follower that two or more users have in common. (Plural: mufos)
That guy is a real jerk, and I'm really glad we have no mufos.
by Push the bully March 13, 2017
Get the Mufo neck gaiter and mug.
legend has it this name was once a nickname for a great man but now many people have forgotten what it stands for.
But itelligence tells me a "mufo" can be:

Any male that is always right, funny and is often mistaken for a god. This things are also there only downside. Often pet named as:

Moof
Mufie
Mufadoodle
and Mufifi
"Wow! He is one of those Mufo's"

OR

"GOD! Why are you always right!"
"yes i am, and because i'm a mufo"
by Mufo, the original May 29, 2008
Get a Mufo mug for your Aunt Julia.