A cruel and unusual twist on the commonly-known phrase "Hostess with the Mostest", which is normally used to describe either a) the Denny's Hostess with the biggest rack...or b) the Hostess that you'd mostest like to anally violate. To the dismay of male chatters around the world, this phrase is used to symbolize many an AOL woman, who not only have an unhealthy desire to accumulate more Twinkies and Suzy-Q's than any other household on the block, but use their impressive cache of baked goods to provide sustenance for the hours upon hours they spend in chatrooms.
JWeed439: "Yo Rylie...have you seen the size of the ass on Jenny lately?" Rylie: "Dude. How can you miss it. She's gotta be the Mostest with the Hostess."
by JWeed439 August 19, 2011