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A short stop at the greatest fast-food restaurant known to God or man, Mighty Taco. This "run" is most often in response to the combination of a near-empty stomach and a near-empty wallet, esp. on the spur of the moment. This delicious phenomenon is known only among natives of Buffalo, NY.
"Hey man, I got the munchies."

"Yeah, me too, let's make a Mighty Run."
by ZeeMan November 09, 2007
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