Top definition
A condition where the person at hand can't resist rooting for the underdog. Usually accompanied by a life of high dreams and much failure.
Dude, why does Ronnie always pick the Timberwolves on 2k11? They suck!

It's not his fault, they guys got a serious case of Mighty Ducks syndrome.

Oh. I see. Poor Ronnie.
by Addedoo May 31, 2011
Get the merch
Get the Mighty Ducks syndrome neck gaiter and mug.
Apr 21 Word of the Day
I've been jabbed
by Francesco II March 20, 2021
Get the mug
Get a jabbed mug for your barber Abdul.