When an overload of memes causes you to orgasm. Multiple memegasms in a row may lead to; spontaneous laughing, shortness of breath, and addiction

when you're hungover as shit after a spending a night drunk as a skunk

1. An internet meme and name for the sounds that a girl gamer (usually with big boobs) makes when she is really excited.

2. The act of splooging one's self when getting all hot and bothered by a girl gamer.

When a noob joins a group and unloads every single meme they have saved in one shot !