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Psilocybin containing mushrooms that are used recreationally to attain a "high". Nickname comes from Nintendo's classic game, Mario, where Mario and Luigi eat various mushrooms to attain either an extra life, a "1UP", or an extra hit.
"Hey man, those Mario treats kicked my ass last night."
"Yeah, I was tripping pretty hard."
by Hippiekid42 June 17, 2009
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