One day, some stoned happy chappy was thinking of things that rhymed with dandruff, and by some happy coincidence, along came a man inflicted with the 'druff, to which stoned happy chappy cried, 'Mandruff!'
And so it was. Do you see?
Hairdresser: ah jeez, your head is mandruff central, dude. You ever thought about modelling for christmas cards?
Dude: Oh christ no!
by Nat October 23, 2004
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Dandruff inconveniently located on the head of an older man.
"Should I give that homeless guy some money?"

"No way, he has mandruff."
by M4RC0 D April 13, 2010
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Dried semen in hair that looks just like dandruff. But isn't.
Is that mandruff in your hair or were you just really excited about your eggs n' grits?

Hey, you might not want to ask her out. She's got bad mandruff. On second thought, maybe you should.
by MaxRocket December 30, 2015
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dead skin, concealed beneath facial hair, that flakes away when you play with it, leaving a trail of snow down the front of your shirt. very similar to the concept of dandruff, but mostly only applicable to men.
dude, you've got mandruff. shampoo your face.
by cunning stunts September 29, 2009
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