Only the most courageous people can say this... to the president of the united fucking states. Also has become a meme.
Person 1: As I was saying-
Person 2: *interrupts about five thousand times*
Person 1: Will you shut up, man?
by alksjfhaksdfh September 30, 2020
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One of the most memorable lines from the first Presidential Debate of the 2020 US election. After constant interruption by then President Trump, former Vice President Biden retorted "Will You Shut Up Man?".
"Who is on your list Joe?"
"Will you shut up man?"
by George's_Bush March 04, 2021
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A phrase used by Antiguan males to warn people that they are not one to be played with or taken lightly.
Example

John Doe 1: * bumps into Dario at a party* and does not apologize.

Dario: Barse, you just bumped into me and didn't say sorry. A wan fuck up man me be na boss.

John Doe: * shivers* I am sorry sir. *retreats*

Confrontation Averted
by CherylBigSon March 22, 2020
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The expression "Yo-Dudes" uses to scare 13-years-old "Yo-Dudes".
by Delf June 23, 2003
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Your tellin ya boy not to mess like with the ladies or on a job interview
"Yo Man Don't Fuck Up that girl is fine"
by : P ya right May 03, 2006
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