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Main Love Interest.
The (usually primary) character in a work of fiction who is meant to be the true love of the protagonist. This especially applies to genres where there are many possible pairings, the purest example being harem anime/manga.
In the series Love Hina, Naru Narusegawa is the MLI of Keitaro Urashima.
by Sendouka January 09, 2010
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A large romanian teddybear, filled with crack to mislead ones parents.
Me and my friends cut mli open and had a good time.
by ShinDeluxe April 30, 2005
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my life is supreme

used when one thinks highly of what is going on in their own life, often better than those around them.

sarcastically used like fml or iflml
Today, I was on the phone with my best guy friend, who I have loved for years. I was talking about school and all of a sudden he said "I love you." I flipped out saying "Oh my god, oh my god. I love you, too!" He responded with "what?" He was talking to his mom, who was walking out the door. MLIS.

Roommate one: Gosh, Rachel, it seems like everything in my life is just going wrong. I just can't catch a break. Can I vent to you?
Rachel: I mean if you want... but I'm not sure how much I will be able to help because MLIS!
by BetaLambda June 04, 2009
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