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A person who thinks that people want, or need to hear what they have to say, or what they think about any situation whether it directly involves, or has nothing to do with them at all. The majority of the time what they have to say is in fact ignorant bullshit, and the world would have been a better place if this person had not opened their mouth at all.
Kanye West Syndrome example 1:

The 'rapper' stormed the stage just after the first award, for Best Female Video was presented to Taylor Swift at the VMA's. He cut the teen singer off, grabbing the mic and protesting in support of Beyoncรฉ.

"I'm sorry, but Beyoncรฉ had one of the best videos of all time," he proclaimed as B looked on from the crowd, stunned. (This is the exact moment where Kanye West Syndrome is evident. What makes him think that his opinion is important or valued? It's the syndrome that makes him feel as though the mass of people gathered for this ceremony came to hear his opinion and appreciate him interrupting poor Taylor's acceptance speech.)
by Willisrl October 11, 2009
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Someone suffering from this disease may think that they are more important than everyone else, and or that they deserve better and special privilege. When. In fact, they're not, and they don't.
Amber: Did you hear that Charles wants to arrive via helicopter?

Ashley: don't pay any attention to him, he's suffering from kanye west syndrome
by The petty one March 05, 2017
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