To pursue sexual activity with a person because they are of a different sexuality.
Jeffrey really pulled off a James Charles last night with my cousin who's a lesbian!
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The person GeorgeNotFound is cheating on dream with.
George- *sends ship photo*
James Charles- are we flirting now?
George- Idk @dreamwastaken would be mad
by KarentheGOdd September 22, 2020
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a pedo that sent nudes/asked for nudes to straight underage boys.
disgusting human being.
by tbjdrrcmaw May 27, 2021
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Friend: you remember James Charles l?

Other friend: oh didn't he die?

Friend:no? Ohhh fu..

*smack*
Me: it's not nice to talk about dead people
by Cotton picker owner May 17, 2019
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