Just stating how life is and how it has its ups and downs and somethings just happen.

when you're hungover as shit after a spending a night drunk as a skunk

It be like that sometimes means you're used to being sad or you're used to getting a whole lot of crap on your plate it don't surprise you no more
It be like that sometimes is making a joke out of a situation you're in
Usually a disappointing situation

A phrase used when there’s simply no explanation so it must happen occasionally ; similar to phrase “gonna have to”

Phrase often used to show that you feel sympathy, but don’t care too much about the situation.

honestly, a phrase that can be said in any situation.