Short for "It's A." It was commonly used as slang before the famous 21 Savage interview where he mentioned his knife tattoo.

Popularized by rapper 21 Savage, "issa" is a conjunction of the words "it's" and "a" (pronounced "ah"). Popularly used in 21 Savage internet memes.

slang term highly popularized by rapper, 21 savage. While describing his forehead tattoo in an interview 21 used "Issa" to say "it's a". 21 has lived a rough life through gangs and danger. He has witnessed his best friends death and has been stabbed. This is what provoked his decision to get a tattoo of a knife on his foreheads. Fans thought the tattoo was a cross but weren't sure so it stroked media. 21 was then asked what the tattoo was and simply said, "Issa knife." After this going public meme pages made fun of 21 and showed no mercy. 21 has lived most of his career getting made fun of because of his past, getting made fun of was no big deal. 21 savage remained insulted because the tattoo had a deep meaning to him and fans made fun of it. He then went to create an album named "Issa" and made light of the situation. The album Issa is the rappers most successful album to date. Let's just say 21 won with "Issa".

The greatest guy on earth, a hottie and a true gentleman. He looks good in everything he wears. He's can put a smile on my face no matter what, he made me the happiest person on earth by just being by my side. He would take a bullet for me, beat up the whole world just to win me. He's someone I can trust with everything I've got even my soul. Someone who misses me even when when we're together. He's without a doubt my true love <3

a legendary human who was born to be sexy. Has many different personalties a rough calculating person and also a kind dude with a big heart. Bitches chase him for his Holy cock.

A sexy dude who is a beast at everything and looks like a built version of Tom Cruise.

Issa is a Ghanaian slang word which is derived from "it is a" normally used in conversation to make it more funnier. It was made up buy a character in a popular Ghanaian series.