A drinking game perfected in the East Coast of Canada that combines solitary confinement with liquor. Every participant must drink a handle of hard liquor in 45 minutes while isolated in their own personal room or confined space without any human interaction or communication. (Including cell phones, television, or even talking). The last person to finish their handle loses the game.
"We played Isolation last night.... It got fucking sloppy"
by dc15 October 24, 2009
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The situation when an iPhone- or iPad-addicted person is separated from their device for any length of time. It leads to feelings of fear and awe at the wide world around them they never bother with the rest of the time.
Dave: "Damn it! I've left my iPhone at home! Now I'm totally iSolated!"

Jim: "You're a prick, Dave."
by jimbobsweeney October 07, 2010
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When someone is behind or hidden in alot of situation and discluded or un noticed in alot of situations
Shelly felt very isolated today
by Ron Carol April 17, 2018
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People say that Beth,Meghan, and I are isolated.
Those gilrs Beth, Meghan,and Anoah are so isolated!
by Anoah September 01, 2004
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dope, killa, fresh, urban
this buds isol, we gotta pick up off this guy more often
by isol April 28, 2007
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