When someone is isolated from the real world due to spending a great amount of time playing an online game that they are seriously addicted to.
John has had Gamer's Isolation ever since he started playing World of Warcraft.
by Yep Its Conan January 15, 2010
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An area within the cervix. When the vagina is penetrated and the individual doing the penetrated has a penis of larger stature, you may pass into this area. This hurts the female more than childbirth.
Ouch! You just thrusted into my isolated location. That Fucking Hurt.
by HardCore November 26, 2013
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Occurs when a two person group is partitioned by one party’s separate conversation via phone call or text message using a cellular device.
The conversation was quite riveting until Becky initiated cellular isolation by sexting for the remainder of the evening.
by harlan500 June 17, 2011
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A crappy excuse to tell your boss that you would rather stay at home watching porn and eating that pasta you’ve been stockpiling
Employee: Sorry, I don’t think I can come to work today, I need to self-isolate
Boss: (sarcastically) Right
by massivetraps25 March 19, 2020
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When you eat something crunchy and it's so loud in your head that you are unable to hear what anyone around you is saying. This may be intentionally used as a manner of shutting out the world or simply an unfortunate consequence of cacophonous cuisine.
Teacher: "Can you answer this question?"
Student: "My apologies, I was in the throes of crunchy isolation. What was your question again?"
Teacher: "Who wrote Fed 51?"
Student: "Maybe I should have stayed in my crunchy isolation..."
by f091993 November 17, 2010
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1. The cause of one's inability to remember what day, week or month it is after a week or so straight of being on "Shelter At Home" orders . May also cause people to forget to shower or wear pants or which direction is which.

2. The thing my brain has been living in since this pandemic quarantine started.
I forgot this Sunday was Easter Sunday because my brain is living in an isolation fog.
by Mysteh April 10, 2020
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The friend you bring along to parties, if you're not sure that people you know will be there. This offers you protection against standing alone on the side like a potted plant or being ranted at by drunken tax attorneys.
Steve: You going to Wendy's on saturday, i don't really know anyone else whoose going.
Freida: Yeah, me neither, i'm bringing Tom as isolation insulation.
by CaptainLemming July 26, 2010
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