Its a person that is usually more big than normal ppl. she is usually brought to a party or something and they are used to make a person to look better. So maybe you are one maybe not. Ppl may joke around and say you are the duff duff. Sometimes ppl will be serous when they say that also. Another thing is tht they may not tell u that ur a duff duff.
lol Mia is totally the duff duff, no what abby is!!!! :p
by Krazy💖 September 07, 2017
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1. Bollocks. Rubbish. Not worth a fuck.

2. The bass player of Guns n' Roses, 10 Minute Warning, Velvet Revolver
1. I cant play that duff guitar you bought, its the cheapest lump of shit I've ever seen!

I was late for work again because my duff old Ford Fiesta broke down again!

2. Uh, well... Duff McKagan plays bass.
by Saviour of the real January 19, 2007
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A person who by society's description doesn't fit in with their friend group, being more approachable, and the one to go to ask for their friends numbers.
Guy: Heyyyyy

Duff:(THINKING: OMG HE's TALKING TO ME> HE'S SO HOT) Yes? What

Guy: Well, i was thinking... would you like to...

Duff: Yeah...?

Guy: What's the hot girl on the left that you were talking too's number...?
by satan666jks May 25, 2015
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The pot left over after being "smoked" in a vaporizer.
I'm gonna make some butter with this duff.
by Bititall June 17, 2006
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Stands for Designated Ugly Fat Friend. A term used to describe a hot girls fat friends. Every hot girl has at least 1 Duff. Treating the Duff like a normal person may help your entry to the hot girls Vagina.
Hey, if your in with the Duff, Your in with the stuff!
by twisted_walker November 12, 2006
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Most commonly known as the girl that your hott date has to take along with her to the x dance. Your date won't go without her so she has to come along. The whole time she gets in the way of you two. Duff stands for designated ugly fat friend. Very terrifying moments have been caused by this race of people.
Bess: "Hey, we should go to Mikes this weekend."
Kailey: "Yeah, thats a great idea. We should take someone else, just in case things get a little too weird."
Bess: "Lets take Sarah. Shes always a good conversation peice."
Sarah= DUFF= Ugly, fat, facial hair, and zits
Everything every "man" wants
by Stanely Jr. October 06, 2005
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