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This term is the term used in the Eminem song "My Mom". The definition for this term means you are huffin' ether (cocaine) and puffin' reefer (marijuana).
Bob: Hey Jim didn't see you last night what happened?
Jim: OOOOOOOOOH! Last night I did some coke and weed.
Bob:So you where Huffin' and Puffin'!?!
Jim: Yaaaaa.
by Japan Bubbles May 26, 2009
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