A very close friend whom you have known for a long time.
"I love my homeslices! We've known eachother

since pre-k!"
by I am your mom's mum. June 04, 2009
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1. Another term for homie, but more personal and often used amongst friends of the highest value.

2. A slice of homie. You have a group of homies, and homeslice is used to address just one of them.
Kristy: "Hey Peta, wanna go skateboarding?"

Peta: "Sure, homeslice."
by Kristy deSM November 08, 2011
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To be used in same context of of Homeboy.
person 1:"Yo my homeslice, holla up in yo face!"
person 2:"Indeed."
by Bish November 24, 2003
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A friend or buddy. Synonym for dude or homie.
Me: What's up Homeslice?
Friend:Oh nothin'. How 'bout you?
by Twinkie Bottlepop November 12, 2012
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Another way of saying homie, or homeboy. This is something people may say if they want to be cool, but the end up just sounding totally cringey. Using the term homeslice is not recommended. The term came around in the early 2000s.
Friend one: "Ayo homeslice! Pull up to Jessica's party tonight!" "It'll be totally lit!"
Friend two: "For sure homeslice! We gonna get so much booty!"
by ExoTiic_Taxez January 01, 2018
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A person you could trust with anything/love in a platonic way; one with whom you roll deep.
Person 1: Oh my God I hate that girl!
Person 2: Don't you dare say that, she's my homeslice.
by SS21 March 03, 2014
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